Although opioid overdose mortality was initially driven by heroin and prescription opioids, fentanyl overdoses have become progressively more important, due to their growing prevalence, difficulty of reversal, and overall lethality171. Treatment with naloxone – an opioid antagonist that can be administered intramuscularly, subcutaneously, intravenously or intranasally – is the substance use disorder most important short‐term […]
